Patient-reported outcomes in patients with type 2 diabetes treated with liraglutide or glimepiride, both as add-on to metformin

Received 18 January 2010; accepted 7 April 2010. published online 05 May 2010.

Abstract

Patient-reported outcomes for liraglutide or glimepiride on metformin were investigated. Patients’ treatment satisfaction on liraglutide was higher than with metformin alone and comparable with glimepiride+metformin. Patients perceived lower frequency of hypoglycaemia than glimepiride+metformin and lower frequency of hyperglycaemia than metformin. Impact of weight on quality of life did not differ.

Keywords: Type 2 diabetes, DTSQ, IWQOL-Lite, Liraglutide, Treatment satisfaction

a Department of Endocrinology and Metabolism C, Aarhus University Hospital, Aarhus, Denmark

b Obesity and Quality of Life Consulting, PLLC, Durham, NC, USA

c Department of Community and Family Medicine, Duke University Medical Center, Durham, NC USA

d Novo Nordisk A/S, Bagsvaerd, Denmark

e Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK

f Oxford Biomedical Research Centre, NIHR, Oxford, UK

Corresponding author. Tel.: +45 89 49 76 51; fax: +45 89 49 76 59.

PII: S1751-9918(10)00048-3

doi:10.1016/j.pcd.2010.04.001

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