Primary Care Diabetes
Volume 4, Issue 1 , Pages 25-32 , April 2010

Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: A population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study

  • Kamlesh Khunti

      Affiliations

    • Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 0116 2525445; fax: +44 0116 2525413.
    • ,
  • Nick Taub

      Affiliations

    • Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, UK
    • ,
  • Jennifer Tringham

      Affiliations

    • Department of Cardiovascular Sciences, University Hospitals of Leicester, UK
    • ,
  • Janet Jarvis

      Affiliations

    • Department of Diabetes, Diabetes Research Unit, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, UK
    • ,
  • Azhar Farooqi

      Affiliations

    • Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, UK
    • ,
  • T. Chas Skinner

      Affiliations

    • Department of Diabetes, Diabetes Research Unit, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, UK
    • ,
  • Melanie J. Davies

      Affiliations

    • Department of Cardiovascular Sciences, University Hospitals of Leicester, UK

Received 2 March 2009 ,Revised 15 October 2009 ,Accepted 8 January 2010.

References 

  1. World Health Organisation: Obesity: Preventing and Managing the Global Epidemic. WHO Technical Report. Series No. 894. Geneva: WHO; 2000;
  2. Yusuf S, Hawden S, Ounpuu S, Bautista L, Franzosi MG, Commerford P, et al. SS INTERHEART Study Investigators Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case control study. Lancet. 2005;366:1640–1649
  3. Ford ES . Risks for all-cause mortality, cardiovascular disease and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care. 2005;28:1769–1778
  4. Gu D, Reynolds K, Wu X, Chen J, Duan X, Reynolds RF, et al. InterASIA Collaborative Group Prevalence of the metabolic syndrome and overweight among adults in China. Lancet. 2005;365:1398–1405
  5. McKeigue PM, Shah B, Marmot MG. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet. 1991;337:382–386
  6. Deurenberg P, Yap M, Van Stveren WA. Body mass index and percent body fat: a meta analysis among different ethnic groups. Int. J. Obes. 1998;22:1164–1171
  7. Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults: executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2497
  8. Alberti KG, Zimmet P, Shaw J. Metabolic syndrome: a new worldwide definition. A consensus statement from the International Diabetes Federation. Diabet. Med. 2006;23:469–480
  9. Grundy SM. Obesity, metabolic syndrome and coronary atherosclerosis. Circulation. 2002;105:2696–2698
  10. Misra A, Wasir JS, Pandey RM. An evaluation of candidate definitions of the metabolic syndrome in adult Asian Indians. Diabetes Care. 2005;28:398–403
  11. Tillin T, Forouhi N, Johnston DG, McKeigue PM, Chaturvedi N, Godsland IF. Metabolic syndrome and coronary heart disease in South Asians. African-Caribbeans and white Europeans: a UK population-based cross-sectional study. Diabetologia. 2005;48:649–656
  12. Valsamakis G, Chetty R, Anwar A, Banerjee AK, Barnett A, Kumar S. Association of simple anthropometric measures of obesity with visceral fat and the metabolic syndrome in male Caucasian and Indo-Asian subjects. Diabet. Med. 2004;21:1339–1345
  13. Han TS, Williams K, Sattar N, Hunt KJ, Lean ME, Haffner SM. Analysis of obesity and hyperinsulinemia in the development of metabolic syndrome: San Antonio Heart Study. Obes. Res. 2002;10:923–931
  14. Office of National Statistics—Population (Census 2001), 2007. Available from http://www.statistics.gov.uk (accessed 17 November 2007).
  15. American Heart Association: screening for diabetes. Position statement. Diabetes Care. 2004;27:S11–S14
  16. Friedewald WT, Levy RJ, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin. Chem. 1972;18:499–502
  17. World Health Organisation: Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycaemia. Report of a WHO/IDF Consultation. Geneva: WHO; 2006;
  18. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44:837–845
  19. Office for National Statistics. NOMIS population database (University of Durham), Labour Market Statistics Group, 2007. Available from http://www.statistics.gov.uk/.
  20. Altman DG. Practical Statistics for Medical Research. CRC Press; 1991;
  21. Kumar BN, Meyer HE, Wandel M, Dalen I, Holmboe-Ottesen G. Ethnic differences in obesity among immigrants from developing countries in Oslo, Norway. Int. J. Obes. 2006;30:684–690
  22. Petersen S, Peto V, Rayner M. Coronary Heart disease statistics. British Heart Foundation Health Promotion Research Group. London: British Heart Foundation; 2004;
  23. Gillies CL, Abrams KR, Lambert PC, Cooper NJ, Sutton AJ, Hsu RT, et al. Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: a systematic review and meta-analysis. BMJ. 2007;334:299
  24. Ilanne-Parikka P, Eriksson JG, Lindstrom J, Hamalainen H, Keinanen-Kiukaanniemi S, Laakso M, et al Prevalence of the metabolic syndrome and its components: findings from a Finnish general population sample and the Diabetes Prevention Study cohort. Diabetes Care. 2004;27:2135–2140
  25. Wannamethee SG, Shaper AG, Lennon L, Morris RW. Metabolic syndrome vs Framingham Risk Score for prediction of coronary heart disease, stroke and type 2 diabetes mellitus. Arch. Intern. Med. 2005;165:2644–2650
  26. Lawlor DA, Ebrahim S, Davey SG. The metabolic syndrome and coronary heart disease in older women: findings from the British Women's Heart and health Study. Diabet. Med. 2004;21:906–913
  27. Foucan L, Hanley J, Deloumaeux J, Suissa S. Body mass index (BMI) and waist circumference (WC) as screening tools for cardiovascular risk factors in Guadeloupean women. J. Clin. Epidemiol. 2002;55:990–996
  28. Davies MJ, Ammari F, Sherriff C, Burden ML, Gujral J, Burden AC. Screening for Type 2 diabetes mellitus in the UK Indo-Asian population. Diabet. Med. 1999;16:131–137

PII: S1751-9918(10)00003-3

doi: 10.1016/j.pcd.2010.01.002

Primary Care Diabetes
Volume 4, Issue 1 , Pages 25-32 , April 2010

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