Primary Care Diabetes
Volume 4 , Pages S43-S56 , April 2010

Practical guidance to insulin management

  • Luigi Meneghini

      Affiliations

    • University of Miami Miller School of Medicine, Miami, Florida, USA
    • Corresponding Author InformationCorresponding author. Luigi Meneghini. Division of Endocrinology & Diabetes, University of Miami School of Medicine, Diabetes Research Institute, 1450 NW 10th Avenue, Miami, Florida 33136, USA. Tel.: +1 305-243-5366; fax: +1 305-243-1200
    • ,
  • Sara Artola

      Affiliations

    • Centro de Salud Hereza I de Madrid, Madrid, Spain
    • ,
  • Salvatore Caputo

      Affiliations

    • Policlinico Gemelli, Università Cattolica, Rome, Italy
    • ,
  • Taner Damci

      Affiliations

    • Istanbul University Cerrahpasa Medical School, Istanbul, Turkey
    • ,
  • Grzegorz Dzida

      Affiliations

    • Medical University of Lublin, Lublin, Poland
    • ,
  • Marcel Kaiser

      Affiliations

    • Private Practice, Frankfurt, Germany
    • ,
  • Kamlesh Khunti

      Affiliations

    • University of Leicester, Leicester, UK
    • ,
  • Andreas Liebl

      Affiliations

    • Diabeteszentrum Fachklinik Bad Heilbrunn, Bad Heilbrunn, Germany
    • ,
  • Robert Ligthelm

      Affiliations

    • EHM Clinic Hoofddorp, Rotterdam, The Netherlands
    • ,
  • Alberto Maran

      Affiliations

    • Università di Padova, Padua, Italy
    • ,
  • Domingo Orozco-Beltran

      Affiliations

    • University Miguel Hernández, Sant Joan d'Alacant, Spain
    • ,
  • Stuart Ross

      Affiliations

    • University of Calgary, Calgary, Canada
    • ,
  • Jean-François Yale

      Affiliations

    • McGill Nutrition Centre, McGill University, Montreal, Canada

References 

  1. Nathan DM , Buse JB , Davidson MB , et al.   Medical management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the Association for the Study of Diabetes . Diabetologia . 2009;52:17–30
  2. American Diabetes Association  . Standards of medical care in diabetes – 2009 . Diabetes Care . 2009;32(Suppl. 1):S13–S61
  3. Rydén L , Standl E , Bartnik M , et al.   Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the Association for the Study of Diabetes (EASD) . Eur. Heart J. . 2007;28:88–136
  4. American Diabetes Association  . Standards of medical care in diabetes – 2008 . Diabetes Care . 2008;31(Suppl. 1):S12–S54
  5. Monnier L , Lapinski H , Colette C . Contributions of fast and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c) . Diabetes Care . 2003;26:881–885
  6. Holman RR , Paul SK , Bethel MA , et al.   10-year follow-up of intensive glucose control in type 2 diabetes . N. Engl. J Med. . 2008;359:1577–1589
  7. Action to Control Cardiovascular Risk in Diabetes Study Group  , Gerstain HC , Miller ME , Byington RP , et al.   Effects of intensive glucose lowering in type 2 diabetes . N. Engl. J Med. . 2008;358:2545–2559
  8. The ADVANCE Collaborative Group . Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes . N. Engl. J Med. . 2008;358:2560–2572
  9. UK Prospective Diabetes Study (UKPDS) Group  . Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) . Lancet . 1998;352:837–853
  10. Russell-Jones D . Blood glucose and bodyweight in type 2 diabetes – are these compatible treatment targets? . Eur. Endocrinol. . 2008;4:31–34
  11. Rosenstock J , Davies M , Home PD , et al.   Insulin detemir added to oral anti-diabetic drugs in type 2 diabetes provides glycemic control comparable to insulin glargine with less weight gain . Diabetes . 2006;55(Suppl. 1):A132
  12. Blonde L , Merilainen M , Karwe V , Raskin P , TITRATE Study Group  . Patient-directed titration for achieving glycemic goals using once-daily basal insulin analogue: an assessment of two different fasting plasma glucose targets – the TITRATE study . Diabetes Obes. Metab. . 2009;11:623–631
  13. Dornhorst A , Lüddeke H-J , Screenan S , et al.   Insulin detemir improves glycaemic control without weight gain in insulin-naïve patients with type 2 diabetes: subgroup analysis from PREDICTIVE™ study . Int. J Clin. Pract. . 2008;62:659–665
  14. Mitri J , Hamdy O . Diabetes medications and body weight . Expert Opin. Drug Saf. . 2009;8:573–584
  15. Williamson DF , Thompson TJ , Thun M , et al.   Intentional weight loss and mortality among overweight individuals with diabetes . Diabetes Care . 2000;23:1499–1504
  16. Prospective Studies Collaboration Whitlock G , Lewington S , Sherliker P , et al.   Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies . Lancet . 2009;373:1083–1096
  17. Anderson JW , Konz EC . Obesity and disease management: effects of weight loss on comorbid conditions . Obes. Res. . 2001;9(Suppl. 4):326S–334S
  18. Anderson G , Bates M , Cova S . Foundations of professional training . Champaign, Illinois: Human Kinetics Publishers; 2007;
  19. World Health Organization  . Self-management support for chronic conditions using 5As . http://www.who.int/diabetesactiononline/about/WHO%205A%20ppt.pdf (accessed 18 December 2009).
  20. Peyrot M , Rubin RR . Behavioral and psychosocial interventions in diabetes: a conceptual review . Diabetes Care . 2007;30:2433–2440
  21. Oldridge NB , Stump TE , Nothwehr FK , Clark DO . Prevalence and outcomes of comorbid metaboloic and cardiovascular conditions in the middle-and older-age adults . J. Clin. Epidemiol. . 2001;54:928–934
  22. Norris SL , Zhang X , Avenell A , et al.   Long-term effectiveness of lifestyle and behavioral weight loss interventions in adults with type 2 diabetes: a meta-analysis . Am. J Med. . 2004;117:762–774
  23. Daly A . Use of insulin and weight gain: optimizing diabetes nutrition therapy . J. Am. Diet. Assoc. . 2007;107:1386–1393
  24. Hermansen K , Davies M , Derezinski T , et al.   A 26-week randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naïve people with type 2 diabetes . Diabetes Care . 2006;29:1269–1274
  25. Korytkowski M . When oral agents fail: practical barriers to starting insulin . Int. J Obes. Relat. Metab. Disord. . 2002;26(Suppl. 3):S18–S24
  26. Williamson DF , Pamuk E , Thun M , et al.   Am. J Epidemiol. . 1995;141:1128–1141
  27. Meneghini LF , Dornhorst A , Sreenan S . PREDICTIVE Study Group . Curr. Med. Res. Opin. . 2009;25:1029–1035
  28. Meneghini L , Koenen C , Weng W , Selam JL . The usage of a simplified self-titration dosing guideline (303 Algorithm) for insulin detemir in patients with type 2 diabetes – results of the randomized, controlled REDICTIVE 303 study . Diabetes Obes. Metab. . 2007;9:902–913
  29. Levemir® EU Summary of Product Characteristics.
  30. Davies M , Storms F , Shutler S , et al.   Improvement of glycemic control in subjects with poorly controlled type 2 diabetes: comparison of two treatment algorithms using insulin glargine . Diabetes Care . 2005;28:1282–1288
  31. Rosenstock J , Davies M , Home PD , et al.   A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naïve people with type 2 diabetes . Diabetologia . 2008;51:408–416
  32. Philis-Tsimikas A , Charpentier G , Clauson P , et al.   Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly controlled type 2 diabetes . Clin. Ther. . 2006;28:1569–1581
  33. Riddle MC , Rosenstock J , Gerich J . Insulin Glargine 4002 Study Investigators, The treat-to target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients . Diabetes Care . 2003;26:3080–3086
  34. Anstine D , Grinenko MD . Rapid screening for disordered eating in college-aged females in the primary care setting . J. Adolesc. Health . 2000;26:338–342
  35. Freund KM , Graham SM , Lesky LG , Moskowitz MA . Detection of bulimia in a primary care setting . J. Gen. Intern. Med. . 1993;8:236–242
  36. McNulty PAF . Prevalence and contributing factors of eating disorder behaviors in active duty Navy men . Mil. Med. . 1997;162:753–758
  37. Cotton MA , Ball C , Robinson P . Four simple questions can help screen for eating disorders . J. Gen. Intern. Med. . 2003;18:53–56

PII: S1751-9918(10)60008-3

doi: 10.1016/S1751-9918(10)60008-3

Primary Care Diabetes
Volume 4 , Pages S43-S56 , April 2010

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