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A Colombian diabetes risk score for detecting undiagnosed diabetes and impaired glucose regulation

  • Noël Christopher Barengo
    Correspondence
    Corresponding author at: Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, AHC2, Miami, FL 33199, USA.
    Affiliations
    Observatorio de Diabetes de Colombia, Organización para la Excelencia de la Salud, Colombia

    Department of Medical and Population Health Sciences Research, Herbert Wertheim College of Medicine, Florida International University, Miami, USA
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  • Diana Carolina Tamayo
    Affiliations
    Observatorio de Diabetes de Colombia, Organización para la Excelencia de la Salud, Colombia
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  • Teresa Tono
    Affiliations
    Observatorio de Diabetes de Colombia, Organización para la Excelencia de la Salud, Colombia
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  • Jaakko Tuomilehto
    Affiliations
    Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland

    Department of Vascular Prevention, Danube-University Krems, Krems, Austria

    Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia

    Dasman Diabetes Institute, Dasman, Kuwait
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Published:October 07, 2016DOI:https://doi.org/10.1016/j.pcd.2016.09.004

      Highlights

      • The ColDRISC is a simple and inexpensive screening test for Type 2 diabetes mellitus in Colombia.
      • The ColDRISC can be used in clinical practice to identify undetected abnormal glucose tolerance.
      • The ColDRISC may reduce the number of invasive glucose tests required in the general population.

      Abstract

      Aims

      (i) To develop a diabetes mellitus risk score model for the Colombian population (ColDRISC); and (ii) to evaluate the accuracy of the ColDRISC unknown Type 2 diabetes mellitus

      Methods

      Cross-sectional screening study of the 18–74 years-old population of a health-care insurance company (n = 2060) in northern Colombia. Lifestyle habits and risk factors for diabetes mellitus were assessed by an interview using a questionnaire consisting of information regarding sociodemographic factors, history of diabetes mellitus, tobacco consumption, hypertension, nutritional and physical activity habits. Anthropometric measurements and an oral glucose tolerance test were taken. The sensitivity and the specificity, receiver-operating characteristic (ROC) curves, were calculated for the ColDRISC and FINDRISC.

      Results

      The area under the ROC curve for unknown Type 2 diabetes mellitus was 0.74 (95% CI: 0.70–0.79) for the ColDRISC and 0.73 for the FINDRISC (95% confidence intervals [CI] 0.69–0.78). Using the risk score cutoff value of 4 in the ColDRISC to detect Type 2 diabetes mellitus resulted in a sensitivity of 73% and specificity of 67%.

      Conclusions

      The characteristics of the ColDRISC show that it can be used as a simple, safe, and inexpensive test to identify people at high risk for Type 2 diabetes mellitus in Colombia.

      Keywords

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