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The association between dietary inflammatory index and metabolic syndrome components in Iranian adults

  • Leila Nikniaz
    Affiliations
    Tabriz Health Services Management Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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  • Zeinab Nikniaz
    Correspondence
    Corresponding author.
    Affiliations
    Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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  • Nitin Shivappa
    Affiliations
    Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA

    Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA

    Connecting Health Innovations LLC, Columbia, SC 29201, USA
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  • James R. Hébert
    Affiliations
    Cancer Prevention and Control Program, University of South Carolina, Columbia, SC 29208, USA

    Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA

    Connecting Health Innovations LLC, Columbia, SC 29201, USA
    Search for articles by this author
Published:August 01, 2018DOI:https://doi.org/10.1016/j.pcd.2018.07.008

      Highlights

      • Association between the dietary inflammatory index (DII) and metabolic syndrome (MetS) was investigated cross-sectionally.
      • Higher DII score was significantly associated with MetS.
      • After adjustment, participants in the highest quartile of DII score had significantly higher FBG.
      • There were not significant association between DII and liver enzymes level.

      Abstract

      Aims

      Investigating the association between the dietary inflammatory index (DII®) and metabolic syndrome (MetS) components and liver enzymes in Iranian population.

      Methods

      The present cross-sectional study consist of 606 participants from East-Azarbaijan-Iran. The MetS status was determined using ATPIII NCEP criteria. Moreover, liver enzymes including alanine aminotransferase and aspartate aminotransferase were measured. The DII was calculated according to Shivappa et al. method using a validated quantitative FFQ. Logistic regression was used to determine the association between DII and MetS.

      Results

      About 34.3% of the participants had metabolic syndrome. Higher DII score was significantly associated with MetS [OR: 2.26 (95% CI: 1.03, 4.92)] after adjusting for covariates. After adjustment, participants in the highest quartile of DII score had significantly higher FBG [OR: 2.56 (95% CI: 1.00, 7.05)] compared with the participants in the lowest quartile of DII score. No other significant association was observed between DII and liver enzymes level and other MetS components (P > 0.05).

      Conclusions

      The results showed that the DII score was associated with overall MetS and FBG, after adjusting for all covariates. For precise conclusion there is a need for longitudinal studies with larger sample size and considering more food parameters.

      Keywords

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