- •Over half deaths in Type-2 diabetes patients are related to cardiovascular diseases.
- •A cardiovascular risk score merely based on clinical data has poor performance.
- •The atherosclerosis burden score is a strong determinant of cardiovascular events.
- •Screening for subclinical atherosclerosis should be implemented in the routine care.
- IDF Diabetes Atlas.8th ed. International Diabetes Federation, Brussels, Belgium2017
- Roglic G. World Health Organization Global Report on Diabetes. World Health Organization, Geneva, Switzerland2016
- 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD.Eur. Heart J. 2020; 41: 255-323https://doi.org/10.1093/eurheartj/ehz486
- Prediction models for the risk of cardiovascular disease in patients with type 2 diabetes: a systematic review.Heart. 2012; 98: 360-369https://doi.org/10.1136/heartjnl-2011-300734
- The validation of cardiovascular risk scores for patients with type 2 diabetes mellitus.Heart. 2015; 101: 222-229https://doi.org/10.1136/heartjnl-2014-306068
- The atherosclerosis burden score (ABS): a convenient ultrasound-based score of peripheral atherosclerosis for coronary artery disease prediction.J. Cardiovasc. Transl. Res. 2015; 8: 138-147https://doi.org/10.1007/s12265-015-9617-5
- Ultrasonic tissue characterization of carotid plaque improves the prediction of cardiovascular events in diabetic patients: a pilot study.Diabetes Care. 2012; 35: 2640-2646https://doi.org/10.2337/dc12-0331
- American heart association council on peripheral vascular disease, council on epidemiology and prevention, council on clinical cardiology, council on cardiovascular nursing, council on cardiovascular radiology and intervention, and council on cardiovascular surgery and anesthesia, measurement and interpretation of the ankle-brachial index: a scientific statement from the American heart association.Circulation. 2012; 126: 2890-2909https://doi.org/10.1161/CIR.0b013e318276fbcb
- Swedish National Diabetes Register, Risk prediction of cardiovascular disease in type 2 diabetes: a risk equation from the Swedish National Diabetes Register.Diabetes Care. 2008; 31: 2038-2043https://doi.org/10.2337/dc08-0662
- Cardiovascular prognosis in patients with type 2 diabetes: contribution of heart and kidney subclinical damage.Am. Heart J. 2015; 169: 108-114.e7https://doi.org/10.1016/j.ahj.2014.09.012
- Carotid plaque calcification predicts future cardiovascular events in type 2 diabetes.Diabetes Care. 2015; 38: 1937-1944https://doi.org/10.2337/dc15-0327
- Use of vascular assessments and novel biomarkers to predict cardiovascular events in type 2 diabetes: the SUMMIT VIP study.Diabetes Care. 2018; 41: 2212-2219https://doi.org/10.2337/dc18-0185
- Contemporary model for cardiovascular risk prediction in people with type 2 diabetes.Eur. J. Cardiovasc. Prev. Rehabil. Off. J. Eur. Soc. Cardiol. Work. Groups Epidemiol. Prev. Card. Rehabil. Exerc. Physiol. 2011; 18: 393-398https://doi.org/10.1177/1741826710394270
- The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56).Clin. Sci. 2001; 101: 671-679https://doi.org/10.1042/cs1010671
- An Australian cardiovascular risk equation for type 2 diabetes: the Fremantle Diabetes Study.Intern. Med. J. 2010; 40: 286-292https://doi.org/10.1111/j.1445-5994.2009.01958.x
- The Framingham and UK Prospective Diabetes Study (UKPDS) risk equations do not reliably estimate the probability of cardiovascular events in a large ethnically diverse sample of patients with diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation (ADVANCE) study.Diabetologia. 2010; 53: 821-831https://doi.org/10.1007/s00125-010-1681-4
- Performance of cardiovascular disease risk scores in people diagnosed with type 2 diabetes: external validation using data from the national Scottish diabetes register.Diabetes Care. 2018; 41: 2010-2018https://doi.org/10.2337/dc18-0578
- Prevalence, vascular distribution, and multiterritorial extent of subclinical atherosclerosis in a middle-aged cohort: the PESA (Progression of Early Subclinical Atherosclerosis) study.Circulation. 2015; 131: 2104-2113https://doi.org/10.1161/CIRCULATIONAHA.114.014310
- Clinical utility of carotid ultrasonography in the prediction of cardiovascular events in patients with diabetes: a combined analysis of data obtained in five longitudinal studies.J. Atheroscler. Thromb. 2018; 25: 1053-1066https://doi.org/10.5551/jat.43141
- Ankle-brachial index, toe-brachial index, and cardiovascular mortality in persons with and without diabetes mellitus.J. Vasc. Surg. 2014; 60: 390-395https://doi.org/10.1016/j.jvs.2014.02.008
- The prognosis of diabetic patients with high ankle-brachial index depends on the coexistence of occlusive peripheral artery disease.J. Vasc. Surg. 2011; 53: 984-991https://doi.org/10.1016/j.jvs.2010.10.054
- Critical analysis and limitations of resting ankle-brachial index in the diagnosis of symptomatic peripheral arterial disease patients and the role of diabetes mellitus and chronic kidney disease.J. Vasc. Surg. 2020; 71: 937-945https://doi.org/10.1016/j.jvs.2019.05.050