Highlights
- •Glucose levels per se are involved in the high caries experience in diabetics, not just hyposalivation.
- •Increases in A1c and fasting blood glucose impact the number of root caries lesions.
- •Salivary glucose levels are correlated with a higher number of active coronal caries in diabetics.
Abstract
Aims
A previous meta-analysis showed that individuals with Type 2 diabetes mellitus (T2D)
have a greater chance of developing both coronal caries and root caries than systemically
healthy ones, which can be influenced by hyperglycemia per se. This study aimed to
associate blood and salivary glucose levels with caries.
Methods
This research is a subset of a cross-sectional study. N = 39 individuals underwent
a dental examination and salivary glucose, fasting blood glucose (FBG) and glycated
hemoglobin (A1c) measurements.
Results
The prevalence of active coronal caries was 10.2%, and that of root caries was 20.5%.
A1c and FBG averages were higher in individuals with root caries (9.75 ± 1.71 and
186.3 ± 62.5) than without (7.01 ± 2.23 and 115.1 ± 48.6; p < 0.05). Individuals with
T2D showed weak correlation of salivary glucose and number of active coronal caries.
Significant correlations were observed between salivary and blood glucose. There was
relevance of A1c (0.53; CI=0.124–0.941; p = 0.01) and FBG (0.019; CI=0.006–0.033;
p = 0.006) toward the increased number of root caries lesions, even after adjustment
for salivary flow and age.
Conclusion
Blood glucose levels are associated with an increased number of root caries in adults
with or without T2D. In individuals with T2D, salivary glucose was correlated with
active coronal caries. Additional studies are needed to support this association.
Keywords
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Article info
Publication history
Published online: November 24, 2022
Accepted:
November 21,
2022
Received in revised form:
November 15,
2022
Received:
September 19,
2022
Identification
Copyright
© 2022 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.
