Commentary| Volume 17, ISSUE 2, P200-201, April 2023

Sleep and probiotics in diabetes management

Published:February 11, 2023DOI:


      • Imbalances in the gut microbiota may lead to the development and progression of diabetes.
      • Sleep disorders are very prevalent in individuals with diabetes and can be related to a worse prognosis for this disease.
      • Probiotics have been linked to improvements in sleep and glucose and high density lipoprotein cholesterol levels.
      • Probiotic supplementation may be considered to control diabetes, enhance metabolic regulation and sleep quality.


      In this manuscript, we call attention to the importance of investigating affordable strategies to improve the management of diabetes. Studies indicate that imbalances in the gut microbiota may lead to the development and progression of this disease. At the same time, poor sleep and sleep disorders, which are very prevalent in individuals with diabetes, can be related to a worse prognosis for the disease and can be impacted by changes in the intestinal microbiome. A suggested treatment that may be effective in controlling diabetes and improving sleep quality through increased metabolic regulation is probiotic supplementation. Scientific evidence has shown a relationship between the use of probiotics and improvements in sleep, in glucose concentrations, and in the levels of high density lipoprotein cholesterol. We suggest that probiotic supplementation can play an important role in the management of diabetes and sleep disorders in diabetic patients. Further randomized clinical studies should be undertaken to better understand the impact and effectiveness of the use of probiotics in improving sleep and controlling diabetes.


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